急、慢性心功能不全治疗中,除应用强心药物外,经常同时使用利尿剂及血管扩张药物。有时为了减少药物所致的胃肠道反应,还须加用胃复安(灭吐灵),普鲁本辛等药物。如此多的药物同时使用,势必引起药物间的相互作用,尤其安全指数低的药物, 如狄戈辛更易受到影响。本文就狄戈辛,洋地黄毒甙与利尿剂、血管扩张剂、抗心律失常药以及与胃复安、普鲁本辛等的相互作用作一综述。 Urgent and chronic heart failure treatment, in addition to cardiac drugs, often with diuretics and vasodilator drugs. Sometimes in order to reduce the gastrointestinal tract caused by drugs, but also with the use of metoclopramide (metoclopramide), such as drugs such as Prussianxin. The simultaneous use of so many drugs will inevitably lead to the interaction between drugs. In particular, drugs with low safety index, such as Digoxin, are more likely to be affected. This review summarizes the interactions between Digoxin, digoxigenin and diuretics, vasodilators, antiarrhythmic drugs, and metoclopramide and prupincin.