本文对50例尿毒症患者血清进行聚丙酰胺凝胶电泳,结果表明其α~-脂蛋白、部分α_1~-和α_2~-球蛋白明显下降,触珠蛋白、β-脂蛋白明显上升。同时对50例肾病综合征患者血清进行上述电泳,结果表明其白蛋白、部分α_1~-和α_2~-球蛋白明显下降,部分β_2-球蛋白及β-脂蛋白明显上升。对上述变化的机理及临床意义也进行了探讨。 In this paper, 50 cases of uremia patients serum polyacrylamide gel electrophoresis, the results showed that the α ~ - lipoprotein, some α_1 ~ - and α_2 ~ globulin decreased significantly, haptoglobin, β-lipoprotein increased significantly. At the same time, 50 cases of patients with nephrotic syndrome were subjected to the above electrophoresis. The results showed that albumin, some α_1 ~ - and α_2 ~ globulin were significantly decreased and some β_2-globulin and β-lipoprotein were obviously increased. The mechanism of the above changes and clinical significance are also discussed.