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目的探讨糖化血红蛋白(HbAlC)水平与缺血性脑血管病的关系及临床应用价值。方法通过测定脑梗死180例(脑梗合并糖尿病组102例,脑梗非糖尿病组78例)和健康对照组150例的HbA1c浓度水平,并比较分析其在各组间的关系。结果脑梗合并糖尿病组高于脑梗非糖尿病组高于健康对照组,脑梗合并糖尿病患者与脑梗非糖尿病患者组间的HbA1c浓度相比较,差异有统计学意义(P<0.05),脑梗非糖尿病患者组与健康对照组间的HbA1c浓度相比较,差异有统计学意义(P<0.05)。结论糖化血红蛋白(HbAlC)水平的升高与缺血性脑血管病的发生相关,观察糖化血红蛋白的变化对缺血性脑血管病的早期预防具有一定临床应用价值。
Objective To investigate the relationship between the level of HbAlc and ischemic cerebrovascular disease and its clinical value. Methods The levels of HbA1c in 180 cases of cerebral infarction (cerebral infarction with diabetes mellitus in 102 cases, cerebral infarction in 78 cases) and healthy control group (150 cases) were measured and their relationship among different groups was analyzed. Results The levels of HbA1c in patients with cerebral infarction complicated with diabetes mellitus were higher than those without diabetes in the cerebral infarction group. There was significant difference (P <0.05) between the cerebral infarction patients with cerebral infarction and the non-diabetic patients with cerebral infarction (P <0.05) The difference of HbA1c concentration between the non-diabetic group and healthy control group was statistically significant (P <0.05). Conclusions The elevated HbAlc level is associated with the occurrence of ischemic cerebrovascular disease. It is worth to observe the changes of HbAc in the early prevention of ischemic cerebrovascular disease.