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我院自1996年2月—1997年2月,应用米非司酮及低浓度催产素对有妊娠合并症、过期妊娠需适时终止妊娠的100例初产妇,随机分为两组,每组50例,分别称米非司酮组,低浓度催产素组。首先用两种药物促宫颈成熟后再应用5％葡萄糖500ml加催产素2.5—5单位静脉滴注引产。两组促宫颈成熟的结果表明,米非司酮组明显优于低浓度催产素组(P<0.05),两组引产成功率比较,米非司酮组优于低浓度催产素组(P<0.05)。引产开始后临产达到的时间、总产程、产后出血、新生儿Apgar评分与低浓度催产素组无显著性差异(P>0.05)。现将其观察结果报告如下:
In our hospital from February 1996 to February 1997, the application of mifepristone and low concentrations of oxytocin on pregnancy complications, pregnancy termination of pregnancy required timely termination of 100 primipara, were randomly divided into two groups of 50 Cases, respectively, mifepristone group, low concentrations of oxytocin group. First of all, with two kinds of drugs to promote cervical ripening and then applied 500ml 5% glucose plus oxytocin 2.5-5 units intravenous drip induction. Cervical maturation of the two groups showed that the mifepristone group was significantly better than the low concentration oxytocin group (P <0.05), and the mifepristone group was better than the low concentration oxytocin group (P < 0.05). The labor time, total labor and postpartum hemorrhage after initiation of induction of labor were no significant difference (P> 0.05) between Apgar score and low concentration oxytocin group. Now report its observations as follows: