论文部分内容阅读
血小板激活因子(PAF)是由血小板、肾小球内皮、肾小球膜和其它细胞产生的一种磷脂,可促进血小板聚集和肾功能损害。因为溶血性尿毒症综合征(HUS)的特征是血小板的活化及其引起的肾小球内皮细胞的损害,而尿液 PAF浓度可反映肾脏 PAF 的产量,本文对 HUS 急性期和恢复期中尿液 PAF 的浓度进行了测定。病人和方法分别从10例典型的腹泻后HUS 急性期儿童及其中的7例康复后(出院后3
Platelet-activating factor (PAF), a phospholipid produced by platelets, glomerular endothelium, mesangial membranes and other cells, promotes platelet aggregation and impaired renal function. Because hemolytic uremic syndrome (HUS) is characterized by platelet activation and damage caused by glomerular endothelial cells, and urine PAF concentration can reflect the production of renal PAF, this article HUS acute and convalescent urine The concentration of PAF was determined. Patients and Methods From 10 patients with typical acute HUS after diarrhea and 7 of them, respectively, after recovery (3