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舌下片是一种含在口腔舌下用的药片,药物通过口腔粘膜而吸收。被吸收的药物直接进入体循环,分布至全身,无首过作用。不是所有药物都可以舌下给药的,首先要求口腔粘膜吸收良好才适于制成舌下片。药物理化性质与其口腔粘膜吸收有关,特别是与油水分配系数有直接关联,而与药物水中溶解度或油中溶解度的绝
The sublingual tablet is a tablet contained under the tongue of the mouth that is absorbed by the oral mucosa. Absorbed drugs directly into the systemic circulation, distributed to the body, no first aid. Not all drugs can be administered sublingually, first of all require good absorption of the oral mucosa is suitable for the manufacture of sublingual tablets. Physical and chemical properties of the drug and its oral mucosal absorption, especially with the oil-water partition coefficient has a direct correlation with the solubility of the drug water or oil solubility