补硒对克山病病区粮饲养大鼠心肌线粒体单胺氧化酶活性的影响

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90只断乳两周的Spragul-Dawley纯种大鼠,随机分为低硒、补硒及常备饲料三组,分别饲以克山病病区低硒粮(含Se 0.009ppm)、克山病病区低硒粮补亚硒酸钠(含Se 0.232ppm)及常备饲料(含Se 0.169ppm),观察硒对心肌线粒体单胺氧化酶活性(MAO)的影响,结果表明:与补硒和常备饲料组相比,低硒组心肌线粒体MAO活性明显下降。饲喂30,60,90天血浆硒含量和红细胞GSH-Px活性显著下降,补硒组心肌线粒体MAO和红细胞GSH-Px活性接近常备饲料组水平。 Ninety weaned Spragul-Dawley rats were randomly divided into three groups: low selenium (containing Se 0.009ppm), Keshan disease The effect of selenium on myocardial mitochondrial monoamine oxidase activity (MAO) was observed. The results showed that with selenium and feedstuff group phase Compared with the low-selenium group, mitochondrial MAO activity was significantly decreased. Plasma selenium content and GSH-Px activity of erythrocytes decreased significantly at 30, 60 and 90 days of feeding, and activities of mitochondria MAO and erythrocyte GSH-Px in selenium-supplemented group were close to those of the normal feed group.
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