目的 :探讨尿激酶对急性脑梗塞的疗效及安全性。方法 :对发病 2 4h内的急性脑梗塞患者用尿激酶进行静脉溶栓治疗。结果 :6h内进行溶栓有效率 87 5 % ,6～ 12h 77 8% ,而12～ 2 4h ,42 9%。 2 4例中临床治愈 12例 ,显著疗效 5例 ,好转 3例 ,无效 2例 ,死亡 2例。总有效率 83 3%。结论 :尿激酶静脉溶栓治疗急性脑梗塞是目前较为安全而有效的方法之一。 Objective: To investigate the efficacy and safety of urokinase in acute cerebral infarction. Methods: Intravenous thrombolysis was given to urokinase in patients with acute cerebral infarction within 24 hours. Results: The effective rate of thrombolysis within 6 hours was 87.5%, 6-12 h 77 8%, and 12 ~ 24 h 429%. Among 24 cases, 12 cases were clinically cured, 5 cases were markedly cured, 3 cases improved, 2 cases were ineffective and 2 cases died. The total effective rate of 83 3%. Conclusion: Thrombolytic therapy of urokinase for acute cerebral infarction is one of the safe and effective methods.