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目的探讨血液置换应用于血液病患者的临床疗效。方法采用MCS+血细胞分离机按疾病分组选用不同治疗项目对53名血液病患者进行血液置换。结果 53名患者进行了1—5疗程不等共157疗程。与治疗前比较:11名白血病患者WBC明显下降;7名红细胞增多症患者Hb、RBC、Hct均明显下降;4名血栓性血小板减少性紫癜患者P lt上升的差异有统计学意义,6名溶血性贫血患者和3名冷凝集素综合症患者Hb上升的差异有统计学意义,5名巨球蛋白血症和5名多发性骨髓瘤患者血浆中M蛋白明显下降。血液置换治疗总有效率在93.7%—100%。结论血液置换能有效缓解患者血液中因一种成分过高所致的高黏滞综合征;尤其适合于不能耐受药物治疗的老年患者。
Objective To investigate the clinical efficacy of blood replacement in patients with hematological diseases. Methods Fifty-three patients with hematological diseases were treated with MCS + blood cell separator according to different treatment options. Results 53 patients were treated for a period of 1-5 ranging from 157 courses. Compared with those before treatment, WBC in 11 leukemia patients decreased significantly; Hb, RBC and Hct in seven patients with polycythemia were significantly decreased; P lt up in four thrombocytopenic purpura patients was statistically significant, six hemolytic There was significant difference in Hb rise between patients with anemia and 3 patients with cold agglutinin syndrome. M protein in 5 macroglobulinemia patients and 5 patients with multiple myeloma was significantly decreased. The total effective rate of blood replacement therapy is 93.7% -100%. Conclusion Blood replacement can effectively relieve the patient’s blood viscosity caused by a high viscosity syndrome; especially suitable for elderly patients who can not tolerate drug treatment.