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目的探讨动态血清孕酮(progesterone,P)及β-人绒毛膜促性腺激素(β-human chorionic gonadotrophin,β-HCG)值对早期异常妊娠的临床意义。方法对重庆市人口和计划生育科学技术研究院附属医院135例孕龄6～8周伴阴道出血的病例进行血清P及β-HCG值动态监测,按妊娠结局分为先兆流产继续妊娠组、难免流产组、输卵管妊娠组。结果先兆流产继续妊娠组动态血清P及β-HCG值显著高于难免流产组及输卵管妊娠组,差异有统计学意义(P<0.05)。先兆流产继续妊娠组动态血清β-HCG值呈上升趋势,难免流产组动态血清P及β-HCG值呈下降趋势,输卵管妊娠组血P及β-HCG值明显低于先兆流产继续妊娠组及难免流产组,差异有统计学意义(P<0.05)。结论动态监测血清P及β-HCG值对早期异常妊娠的诊断和治疗有重要的临床意义。
Objective To investigate the clinical significance of serum progesterone (P) and β-human chorionic gonadotrophin (β-HCG) in early abnormal pregnancy. Methods Serum levels of P and β-HCG were measured in 135 cases with vaginal bleeding of 6-8 weeks of gestational age in Affiliated Hospital of Population and Family Planning Science and Technology of Chongqing Municipality. According to the pregnancy outcome, it was inevitable to be divided into the follow-up pregnancy group Abortion group, tubal pregnancy group. Results The levels of serum P and β-HCG in threatened abortion pregnancy group were significantly higher than those in the inevitable abortion group and tubal pregnancy group (P <0.05). Threatened abortion continued dynamic pregnancy group serum β-HCG value is rising, it is inevitable that abortion group dynamic serum P and β-HCG value decreased, tubal pregnancy group blood P and β-HCG value was significantly lower than threatened abortion and further pregnancy group and inevitable Abortion group, the difference was statistically significant (P <0.05). Conclusions The dynamic monitoring of serum P and β-HCG values has important clinical significance in the diagnosis and treatment of early abnormal pregnancy.