小蘗硷在19世紀就作为苦味健胃药使用。經許多学者研究,本品尚具有鎮靜、鎮痛作用,能适度抑制植物神經节的兴奋,并能改变心电图、下降血压、增强子宫肌和腸肌的收縮,且毒性很低。在中国目前用于菌痢亦收到良好效果。但对胆汁分泌的影响尚未有过报道。作者进行了动物利胆作用的实驗研究,并使用于临床,观察了225例。 Berberine is used as a bitter stomach medicine in the 19th century. After many scholars study, this product is still sedative, analgesic effect, can moderate inhibition of autonomic ganglia excitement, and can change the electrocardiogram, blood pressure, and enhance contraction of the uterine muscle and intestinal muscle, and low toxicity. Currently used for bacillary dysentery in China also received good results. But the impact on bile secretion has not been reported. The authors conducted an experimental study on the animal gallbladder effect and used it in clinical practice and observed 225 cases.