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目的探讨米非司酮治疗稽留流产患者的疗效。方法 90例稽留流产患者,分成观察组和对照组两组。对照组给予小剂量米非司酮联合米索前列醇;观察组给予大剂量米非司酮联合米索前列醇。结果观察组未服米索前列醇就排出胚胎病例数、阴道出血>100ml病例数、住院时间>3d病例数均少于对照组,差异有统计学意义(P<0.05)。观察组出现副反应率为51.11%与对照组46.67%相比,差异不显著。结论大剂量米非司酮可作为治疗稽留流产患者的给药途径。
Objective To investigate the curative effect of mifepristone on missed abortion patients. Methods 90 cases of missed abortion patients were divided into observation group and control group. The control group was given low dose mifepristone combined with misoprostol; the observation group was given high dose mifepristone combined with misoprostol. Results In the observation group, the number of embryos discharged without misoprostol was significantly lower than that of the control group (P <0.05). The number of vaginal bleeding> 100ml and the length of hospital stay> 3d were less than those of the control group. The incidence of side effects in the observation group was 51.11% compared with 46.67% in the control group, the difference was not significant. Conclusion High-dose mifepristone can be used as a treatment for missed abortion patients.