中枢神经系统发生缺血性损伤后导致很高的死亡率及致残率。为了有效地防治脑缺血损伤,必须尽快恢复缺血脑组织的血液供应。目前临床常采取溶栓、解痉、血管吻合及心肺脑复苏等疗法使阻断的脑动脉血流再通,改善组织的血液供应,但其疗效仍有争议。因而探讨缺血脑组织重灌流的病理生理改变及重灌流时采取的措施倍受重视。多年的实验研究表 The ischemic injury of the central nervous system leads to high mortality and morbidity. In order to effectively prevent and cure cerebral ischemia injury, we must restore the blood supply of ischemic brain tissue as soon as possible. At present, the thrombolytic, antispasmodic, vascular anastomosis, cardiopulmonary resuscitation and other therapies are often used clinically to block the recanalization of the cerebral arteries and improve the blood supply to the tissues. However, its efficacy is still controversial. Therefore, to explore the pathophysiology of ischemic brain reperfusion perfusion and reperfusion perfusion received much attention. Years of experimental research table