中毒性表皮坏死松解症(Toxic epid-ermal necrolysis)简称 TEN。1956年 Lyell 等曾首先报道4例患者。发病均突然,呈急性经过,全身症状严重。主要体征为全身表皮剥离和水疱形成,很似烫伤,故亦名烫伤样皮炎。鉴于本病具有独特的临床和病理组织学表现,国内外学者已从各方面进行研究和探讨。近年来,本病发病率在我区亦有所增加。本文就 TEN 的病因、 Toxic epidermal necrolysis (Toxic epid-ermal necrolysis) referred to as TEN. In 1956, Lyell et al first reported 4 patients. Incidence are sudden, was acute after the systemic symptoms. The main signs of systemic epidermal peel and blister formation, it is similar to scald, it is also known as scalded dermatitis. In view of this disease has a unique clinical and histopathological manifestations, scholars at home and abroad have been from all aspects of research and discussion. In recent years, the incidence of this disease has also increased in our district. This article on the etiology of TEN,