播散性血管内凝血(Disseminated intravascular Coagulation,DIC)可以成为多种疾病的严重并发症。可见于固紫阴性细菌败血症、肿瘤、产科病、毒蛇咬伤、妊娠急性脂肪肝、颅脑外伤和登革热等。近年来发现DIC亦可见于严重的恶性疟疾患者。现将有关文献综述如下: 恶性疟疾并发DIC的机理和诊断恶性疟疾时发生的DIC和其他原因引起的DIC情况一样,表现为血小板减少,凝血酶原时间、部分凝血活素时间和出血时间均延长,血浆纤维蛋白原减少,纤维蛋白降解产物增高,优球蛋白血块溶解时间缩短以及明显的出血倾向或多系统的广泛出血现象。 Dennis(1966)等已经实验证明动物的疟 Disseminated intravascular coagulation (DIC) can be a serious complication of many diseases. Can be found in solid purple-negative bacterial sepsis, cancer, obstetric disease, snake bites, acute fatty liver of pregnancy, traumatic brain injury and Dengue fever. In recent years, DIC also found in patients with severe malaria. The literature is summarized as follows: DIC mechanism of concurrent falciparum and DIC diagnosis of malignant malaria and other causes of DIC caused by the same situation, the performance of thrombocytopenia, prothrombin time, partial thromboplastin time and bleeding time are prolonged , Decreased plasma fibrinogen, increased fibrin degradation products, shorter time to euglobulin clot lysis, and pronounced bleeding tendency or extensive bleeding of multiple systems. Dennis (1966) and others have experimentally proven animal malaria