Vasopressin Signaling Buffers Synaptic Metaplasticity in a Sex-specific Manner

来源 :神经科学通报(英文版) | 被引量 : 0次 | 上传用户:maomao1t
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Social animals prefer to live in groups and transfer social signals to share their physical or psychological distress and seek comfort [1,2].During this process,social buffering is an essential concept in social networks.This refers to the phenomenon wherein the presence of social partners reduces the physiological stress response in a distressed animal [3].This phenomenon exists in humans,non-human primates,rodents,birds,and even zebrafish [3].Stress triggers a comprehensive biological response in the entire organism [4],however,research into social buffering has primarily focused on behavioral changes,endocrine changes,the activation of specific cell ensembles,changes in neural circuits,or changes in intrinsic activity [5,6].In recent years,stress-induced changes in glutamatergic synaptic plasticity,or metaplasticity,have garnered increasing attention.
其他文献
It is widely acknowledged that holistic process-ing is a key characteristic of face perception.Although holistic processing implies the automatic integration of face parts,it is unclear whether such processing requires the awareness of face parts.Here,we
Dear Editor,rnHamanaka et al.first reported semaphorin 6B (SEMA6B)(MIM 608873) as a causative gene for progressive myoclonic epilepsy (PME) in 2020[1].They reported that four variants occurred in the last exon of SEMA6B in five unrelated individuals with
期刊
Schizophrenia (SZ) is a chronic,serious,and recurrent mental illness,characterized by cognitive impairment as the core symptom,which can be an important sign before the onset of psychosis [1].Furthermore,persistent cogni-tive impairment is specific to the
期刊
Dear Editor,rnIt is well-known that pupil size,albeit intrinsically sensi-tive to ambient luminance changes,can be modulated by many cognitive processes,especially those associated with physiological arousal[1].Compatible with this view,when observers are
期刊
Exposure to chronic hypoxia is considered to be a risk factor for deficits in brain function in adults,but the underlying mechanisms remain largely unknown.Since active myelinogenesis persists in the adult central nervous system,here we aimed to investiga
As a major public health problem in modern society,Alzheimer\'s disease (AD) is currently the most widely prevalent neurodegenerative disease,which will indu-bitably increase dramatically in the coming years,unless drugs that can prevent or cure the dis
期刊
Human genetic prion diseases(gPrDs)are directly associated with mutations and insertions in the PRNP(Prion Protein)gene.We collected and analyzed the data of 218 Chinese gPrD patients identified between Jan 2006 and June 2020.Nineteen different subtypes w
There has been a substantial reduction in the rate of recurrent stroke through the identification and management of risk factors including lifestyle management and achiev-ing targets for antithrombotic medication,low-density lipoprotein cholesterol (LDL-C
期刊
Dear Editor,rnAutistic people often show enhanced pitch-processing skills involving complex tones and musical tones.How-ever,when it comes to tones that carry linguistic meaning such as lexical tones in tonal languages and speech intonation,they tend to d
期刊
Over evolution,the human species has acquired higher cognitive function,which helps to distinguish Homo sapiens from other mammals.Particularly,humans have a large neocortex through the evolutionary expansion of the brain,which is believed to be instrumen
期刊