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脓毒症是病原体入侵或条件致病菌进入血液循环所造成的全身炎症反应综合征,当病情控制不佳时,可进展至严重脓毒症、脓毒症休克及多器官功能障碍;目前关于脓毒症早期诊断、预后判断的生物标记物研究很多,大约有200多种,本研究将就脓毒症诊断、预后判断相关标记物可溶性白细胞分化抗原14亚型(sCD14-ST)、可溶性尿激酶型纤溶酶原激活物受体(suPAR)、正五聚蛋白3(PTX3)的研究进展做一综述。
Sepsis is a systemic inflammatory response syndrome caused by the invasion of pathogens or the entry of opportunistic pathogens into the bloodstream and can progress to severe sepsis, septic shock and multiple organ dysfunction when the disease is poorly controlled. Septic early diagnosis, prognostic judgment of biomarkers are many, there are about 200 kinds of this study will sepsis diagnosis, prognosis of markers related to soluble leukocyte differentiation antigen subtype 14 (sCD14-ST), soluble urine The progress of research on supeptin, pentraxin 3 (PTX3) is reviewed.