患者女,23岁,未婚,住院号8343。患者于1979年经确诊为甲状腺机能亢进(甲亢),交替服用他巴唑、甲基硫氧嘧啶、心得安等药物。1年后症状控制,BMR,血T_3,T_4均恢复正常,继续服用维持量他巴唑。1983年12月3日起出现全身乏力、失眠、心悸气促、关节酸痛等症状,于1984年1月9日住院治疗。 体检:体温37.8℃,双眼球轻度突出,两手轻度震颤,颜面及上睑轻度浮肿。全身未见皮疹。双甲状腺Ⅱ°肿大,未及结节,右侧可闻血管杂音。心率120次/分,律齐,心尖区可闻Ⅱ级收缩期吹风样杂音,心界向左轻度扩大。两肺清, Female patient, 23 years old, single, hospital number 8343. Patients in 1979 was diagnosed with hyperthyroidism (hyperthyroidism), alternating with methimazole, methylthiouracil, propranolol and other drugs. Symptom control after 1 year, BMR, blood T_3, T_4 returned to normal, continue to take the amount of methimazole. December 3, 1983 from the onset of generalized fatigue, insomnia, palpitations, shortness of breath, joint pain and other symptoms, in January 9, 1984 hospitalization. Physical examination: body temperature 37.8 ℃, mild eyeballs prominent, his hands mild tremor, facial and upper eyelid mild edema. No skin rash. Double thyroid enlargement Ⅱ °, no nodules, the right can be heard vascular murmur. Heart rate 120 beats / min, law Qi, apical area can be heard Ⅱ grade systolic hair-like murmurs, heart slightly expanded to the left. Two lungs clear,