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目的:评价头孢布烯治疗婴幼儿肺炎的临床疗效和安全性.方法:将50例婴幼儿肺炎患儿随机分为序贯治疗组:26例患儿先以头孢呋辛iv gtt 3d后用头孢布烯po;对照组:24例患儿单用头孢呋辛iv gtt,总疗程均为7～10d.结果:序贯治疗组与对照组临床疗效比较无明显差异,头孢布烯细菌药敏试验结果敏感率为84.62%,较头孢呋辛(61.54%)敏感.头孢布烯无明显不良反应.结论:头孢布烯是治疗婴幼儿肺炎有效、安全的药物.
Objective: To evaluate the clinical efficacy and safety of ceftibuten in the treatment of infantile pneumonia.Methods: Fifty infants with pneumonia were randomly divided into sequential treatment group (n = 26): 26 patients were treated with cefuroxime iv gtt 3d Budeson po; control group: 24 cases of children with single cefuroxime iv gtt, the total course of treatment was 7 ~ 10d.Results: There was no significant difference between the sequential treatment group and the control group, ceftibuten bacteria susceptibility test Results Sensitivity was 84.62%, which was more sensitive to cefuroxime (61.54%) than ceftibuten.Conclusion: Ceftibuten is an effective and safe drug for the treatment of pneumonia in infants and children.