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给两周内无活动性出血的胃十二指肠溃疡患者连续服用甲硝唑三周,总量21克,总愈合率78%(32/41),总有效率为90.2%(37/41),与安慰剂组相比有显著性差异。对十二指肠溃疡的疗效与文献报告的甲氰咪胍3—4周疗法的效果相当而副作用轻微。
Patients with gastroduodenal ulcer who had no active bleeding within two weeks were given metronidazole continuously for three weeks for a total of 21 grams with a total healing rate of 78% (32/41) and a total effective rate of 90.2% (37/41 ), Compared with the placebo group were significantly different. The efficacy of duodenal ulcer and cimetidine reported in the literature 3-4 weeks treatment effect is equivalent and minor side effects.