目的分析重症加强护理病房(ICU)患者发生导管相关性血流感染的影响因素。方法对2014年7月—2016年7月金华市人民医院ICU治疗的960例中心静脉置管患者进行回顾性调查,分析导管相关性血流感染发生率及其影响因素。结果发生导管相关性血流感染45例,感染率为4.69%。不同性别患者导管相关性血流感染率差异无统计学意义(P>0.05);≥50岁组感染率为6.89%,高于<50岁组的3.17%(P<0.05);反复穿刺感染率为11.11%,高于穿刺一次成功的3.80%(P<0.05);置管时间长、置留部位为股静脉的患者导管相关性血流感染率相对较高(均P<0.05)。结论患者年龄、置管时间、置管部位和反复穿刺是发生导管相关性血流感染的影响因素。 Objective To analyze the influencing factors of catheter-related bloodstream infection in intensive care unit (ICU) patients. Methods A retrospective investigation was performed on 960 central venous catheterization patients in ICU of Jinhua People’s Hospital from July 2014 to July 2016. The incidence of catheter-related bloodstream infection and its influencing factors were analyzed. Results 45 cases of catheter-related bloodstream infection occurred, the infection rate was 4.69%. The infection rate of catheter-related bloodstream among different sexes was no significant difference (P> 0.05). The infection rate of ≥50 years old group was 6.89%, which was higher than 3.17% of <50 years old group (P <0.05) (11.11%), which was higher than the successful puncture (3.80%) (P <0.05). The catheter-related bloodstream infection rate was longer in patients who had long catheterization and femoral vein. Conclusion Age, catheterization time, site of catheterization and repeated puncture are the influencing factors of catheter-related bloodstream infection.