妊娠期高血压疾病(HDCP)为妊娠期特有的疾病,我国发病率为9.4%[1]。妊娠20周以后发病者,表现为高血压、水肿、蛋白尿等一系列症状。重度子痫前期是孕产妇和围生儿患病率及病死率的主要原因。子痫前期的病因目前仍不明确,但发病机制已比较明确:血管内皮损伤导致缩血管因子和舒血管因子失衡,出现全身普遍性的小动脉痉挛,脏器功能和 Hypertensive disorder of pregnancy (HDCP) is a unique disease during pregnancy, the incidence of 9.4% in China [1]. The incidence of patients after 20 weeks of pregnancy, manifested as hypertension, edema, proteinuria and a series of symptoms. Severe preeclampsia is the main cause of maternal and perinatal morbidity and mortality. The cause of preeclampsia is still not clear, but the pathogenesis has been more clear: vascular endothelial injury leads to vasoconstrictors and vasodilators imbalance, the emergence of generalized arteriolar spasm, organ function and