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本文旨在确定口服胺碘达隆对WPW综合征并发房颤病人的长期疗效及其与心脏电生理效应的关系。方法:32±14(9～59)岁的10(男6、女4)例曾有自发性房颤伴快速心室率的WPW病人作为研究对象。其中,9例尚有自发性室上性心动过速,2例尚有(心)房扑(动),5例在房颤发作时曾并发心室颤动。试验前平均用过2.7种抗心律失常药无效,试验前停用一切抗心律失常药至少5个半衰期。9例病人先作基础电生理测试。各例用心房期前刺激(S_1S_2)或快速心房起搏诱发房颤。测定房颤或房扑时最短和平均RR间期,然后使之转复为窦性心律。7例病人
This article aims to determine the long-term efficacy of oral amiodarone in patients with WPW syndrome complicated by atrial fibrillation and its relationship with cardiac electrophysiological effects. Methods: A total of 10 (6 males, 4 females) with 32 ± 14 (9 to 59) years old had WPW patients with spontaneous atrial fibrillation and rapid ventricular rate. Among them, 9 patients still had spontaneous supraventricular tachycardia, 2 patients had (heart) atrial flutter (moving), 5 patients had concurrent ventricular fibrillation during atrial fibrillation. The average of 2.7 antiarrhythmic drugs used before the trial was invalid and all antiarrhythmic drugs were discontinued for at least 5 half-lives before the trial. Nine patients first made basic electrophysiological tests. In each case, atrial fibrillation was induced by atrial pre-stimulation (S_1S_2) or rapid atrial pacing. Determination of atrial fibrillation or atrial flutter when the shortest and average RR interval, and then make it into sinus rhythm. 7 patients