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目的 :观察生理盐水清洁灌肠后联合药物保留灌肠和静脉应用抗生素治疗急性细菌性痢疾 (急性菌痢 )疗效和对治疗过程中出现中毒型菌痢和慢性菌痢的影响。方法 :将本院住院治疗的急性菌痢随机抽出生理盐水清洁灌肠联合药物保留灌肠 49例和头孢唑啉钠或氨苄青霉素静脉输液治疗 46例。对比两组疗效和对治疗过程中出现中毒型菌痢和慢性菌痢的患病率影响。结果 :两组在疗效、治疗过程中出现的中毒性菌痢和慢性菌痢患病率有显著性差异 ,前者明显优于后者。结论 :生理盐水清洁灌肠后联合药物保留灌肠 ,直接作用于病变肠道粘膜 ,减少杀死了肠道细菌 ,减少消除了肠道毒素的产生 ,保护肠道粘膜等 ,及时阻止肠道粘膜病变的进一步加重 ,促进肠道病变痊愈 ,有较好临床疗效 ,并减少了中毒型菌痢和慢性菌痢的总体患病率。
OBJECTIVE: To observe the effects of antibiotics in combination with drug retention enema and intravenous antibiotics in the treatment of acute bacillary dysentery (acute bacillary dysentery) and the effects of toxic bacillary dysentery and chronic bacillary dysentery during the treatment. Methods: 49 cases of acute bacillary dysentery hospitalized in our hospital were randomly divided into saline enema cleaning enema (49 cases) and cefazolin sodium or ampicillin intravenous infusion (46 cases). The effects of two groups of curative effects and prevalence of toxic bacillary dysentery and chronic dysentery during treatment were compared. Results: There was a significant difference between the two groups in the incidence of toxic bacillary dysentery and chronic dysentery in the course of treatment and treatment. The former was significantly better than the latter. Conclusion: After the saline enema cleaning enema retention enema, the direct effect on the lesion intestinal mucosa, reducing the killing of intestinal bacteria, reducing the production of intestinal toxins to reduce, protect the intestinal mucosa, and timely prevention of intestinal mucosal lesions Further aggravating and promoting the recovery of intestinal diseases, have better clinical efficacy, and reduce the overall prevalence of dysentery and chronic dysentery poisoning.