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目的探讨组织细胞增生症(LCH)的临床影像学特点。方法回顾性分析11例临床证实的LCH,X线检查11例,CT检查1例,MRI检查1例。结果肺部弥漫网点状阴影6例;肝脾肿大6例。骨骼病变中:虫噬样破坏3例,囊样膨胀性改变3例,广泛溶骨性破坏5例;软组织肿块4例;骨膜反应5例。MRI检查1例,骨骼病变呈稍长T1、长T2信号。结论LCH骨骼影像学表现具有特征性:累及长管骨时,多有骨膜反应;累及脊椎骨时,椎间软骨多不受累;所有骨骼病变均可出现软组织肿块。LCH单系统受累患者临床预后较好。
Objective To investigate the clinical imaging features of histiocytosis (LCH). Methods Retrospective analysis of 11 cases of clinically confirmed LCH, X-ray examination in 11 cases, CT examination in 1 case, MRI examination in 1 case. Results Pulmonary diffuse dot shadow in 6 cases; hepatosplenomegaly in 6 cases. Skeletal lesions: worm-like destruction in 3 cases, cystic swollen changes in 3 cases, extensive osteolytic destruction in 5 cases; soft tissue mass in 4 cases; 5 cases of periosteal reaction. MRI examination in 1 case, skeletal lesion was slightly longer T1, T2 signal. Conclusions The imaging features of LCH skeletal bone are characteristic. When the long bones are involved, there are many periosteal reactions. When involving the vertebra, most of the intervertebral cartilages are not affected. Soft tissue mass may appear in all skeletal lesions. LCH single system involvement of patients with better clinical prognosis.