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目的：分析总结胆红素与NSE联合测定在新生儿黄疸期的临床价值。方法选择在笔者所在医院出生的86例新生儿，随机分为对照组(健康的新生儿)43例和试验组(发生黄疸的新生儿)43例，观察试验组治疗前后胆红素与NSE的含量变化。结果试验组43例新生儿治疗前后胆红素、NSE含量显著下降，治疗前后比较差异有统计学意义( PO．05)。结论新生儿黄疸期血胆红素与N S E联合测定具有很好的灵敏度，通过观察动态变化规律，探讨其与病情演变、治疗预后的相关性临床意义。“,”Objective To investigate the clinical value of bilirubin with NES detection in neonatal jaundice.Methods Selected 86 newborns were divided into healthy group(n=43) and jaundice group (n=43). The concentration of bilirubin and NES in blood were detected before and after treatment. Results Compared with baseline, both blood concentrations of bilirubin and NES were significantly decreased after treatment in jaundice group (P0.05). Conclusion The detection of bilirubin with NES has important clinical value for neonatal jaundice, can improve the accuracy of the diagnosis,help providing guidance for the treatment and prognosis of the disease.