近年有关ＶＥＧＦ的研究进展迅速 ,发现其在肿瘤的发生发展中起着极其重要的作用。肿瘤的新生血管形成 ,不仅为肿瘤的增长提供营养和气体交换 ,而且也是肿瘤细胞浸润、转移的直接途径。肿瘤血管的启动是由肿瘤细胞分泌的促内皮细胞增殖和迁移的多种血管生长因子所诱发 ,诸如Ｖ In recent years, the research on VEGF has progressed rapidly and found that it plays an extremely important role in the occurrence and development of tumors. Tumor neovascularization, not only for the growth of the tumor to provide nutrition and gas exchange, but also a direct way of tumor cell invasion and metastasis. Vascularization is initiated by a variety of vascular growth factors secreted by tumor cells that promote endothelial cell proliferation and migration, such as V