论文部分内容阅读
[目的]探讨复方苦参注射液联合顺铂治疗恶性腹腔积液的疗效。[方法]62例患者随机分为治疗组(34例)和对照组(28例)。2组腹腔内均注入顺铂40 mg溶于0.9%氯化钠40 ml中。治疗组同时加复方苦参注射液40 ml腹腔注入。1周1次,连用4次为1个疗程。观察2组的腹水消失情况及KPS评分变化情况。[结果]治疗组完全缓解9例,部分缓解17例,无效8例。对照组依次为5、9、14例。2组总有效率及治疗前后KPS评分比较差异均有统计学意义(P<0.05,<0.01)。[结论]复方苦参注射液联合顺铂腹腔内注射治疗恶性腹腔积液可明显提高腹腔化疗的疗效。
[Objective] To investigate the curative effect of Compound Kushen Injection and Cisplatin in the treatment of malignant ascites. [Methods] 62 patients were randomly divided into treatment group (34 cases) and control group (28 cases). Two groups were intraperitoneally injected cisplatin 40 mg dissolved in 0.9% sodium chloride 40 ml. The treatment group also added compound Kushen injection 40 ml intraperitoneal injection. 1 week, once every 4 times for a course of treatment. The disappearance of ascites and changes of KPS score in 2 groups were observed. [Results] The treatment group completely relieved in 9 cases, partially relieved in 17 cases and ineffective in 8 cases. The control group followed by 5,9,14 cases. The total effective rate of the two groups and KPS scores before and after treatment were significantly different (P <0.05, <0.01). [Conclusion] Compound Kushen injection combined with cisplatin intraperitoneal injection in the treatment of malignant ascites can significantly improve the efficacy of intraperitoneal chemotherapy.