论文部分内容阅读
目的:观察胃安合剂对实验性大鼠胃溃疡的预防及治疗作用。方法:用利血平、乙酸和水浸应急的方法建立大鼠胃溃疡模型,以胃痛宁片为阳性对照,以溃疡指数和溃疡抑制率为指标,评价其作用。结果:与模型组比较,胃安合剂能显著降低3种胃溃疡模型的溃疡指数(P<0.01或<0.05)。其中中、高剂量组效果与胃痛宁组相当。结论:胃安合剂对大鼠胃溃疡模型具有明显的预防和治疗作用。
Objective: To observe the preventive and therapeutic effect of Weianan on experimental gastric ulcer in rats. Methods: The rat model of gastric ulcer was established by reserpine, acetic acid and water immersion method. Weitongning tablet was used as positive control, ulcer index and ulcer inhibition rate were used as indexes to evaluate the effect. Results: Compared with the model group, Weian Mixture can significantly reduce the ulcer index of the three models of gastric ulcer (P <0.01 or <0.05). Among them, the effect of medium dose and high dose is similar to that of Weitongning. Conclusion: Weian Mixture has obvious preventive and therapeutic effects on gastric ulcer model in rats.