论文部分内容阅读
以健康青年学生（ＨＢｓＡｇ、抗－ＨＢｓ和抗－ＨＢｃ均阴性）为观察对象，研究了抗－ＨＢｓ下降规律。结果表明，保护水平的抗－ＨＢｓ（＞１０ｍＩＵ／ｍｌ）的持续时间与３针免疫后抗－ＨＢｓ峰值密切相关，而抗－ＨＢｓ的下降率与峰值无关。在此基础上又进行了回归分析，得到预测模型：Ｌｏｇ（ＭＩＵ）＝３．３０７７—０．３４２６Ｔ，换言之，由于ＭＩＵ值＝１０ｍＩＵ／ｍｌ为阴转临界点，可用此方程预测某个体阴转的时间：Ｔ＝［（ａ—Ｌｏｇ（ＭＩＵ）］／０．３４２６＝（ａ—１）／０．３４２６，在其阴转之前加强接种，对合理安排加强免疫是非常有意义的。
To healthy young students (HBsAg, anti-HBs and anti-HBc were negative) as the object of observation, anti -HBs decline. The results showed that the duration of protection against anti-HBs (> 10mIU / ml) was closely related to the peak of anti-HBs after 3-pin immunization, while the rate of decrease of anti-HBs was independent of the peak. On the basis of this, a regression analysis was carried out to obtain a prediction model: Log (MIU) = 3.3077-0.3426T, in other words, since the MIU value = 10 mIU / ml is the negative transition point, this equation can be used to predict the overcast of an individual Of the time: T = [(a-Log (MIU)] / 0.3426 = (a-1) /0.3426. It is very meaningful to have a reasonable arrangement for boosting vaccination.