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目的:虽然目前腹腔镜下的三角吻合和重叠式三角吻合术已逐步应用于完全腹腔镜左半结肠癌根治术中,但其疗效对比评估却并未在已发表文献中提及。故本研究探讨重叠式三角吻合技术在完全腹腔镜左半结肠切除术中应用的安全性和可行性。方法:采用回顾性队列研究方法,回顾分析中国医学科学院北京协和医学院肿瘤医院结直肠外科2017年5月至2020年10月期间,行完全腹腔镜左半结肠切除术患者的临床病理资料。病例入组标准:(1)年龄为18~75岁;(2)体质指数(BMI)18.5~30 kg/mn 2;(3)术前结肠镜病理证实为降结肠及乙状结肠近段的结肠腺癌。排除标准:(1)结直肠多原发癌;(2)患有糖尿病、免疫系统疾病、血液病未控制或控制不佳者;(3)伴有严重肠梗阻患者;(4)左侧横结肠癌及结肠脾曲部位腺癌;(5)经胸腹盆部增强CT发现肝脏、肺及其余脏器的远处转移者。根据以上标准,共115例左半结肠癌患者入组。根据消化道重建方式不同,分为重叠式三角吻合组(60例)和传统三角吻合组(55例)。比较并分析腹腔镜下两种消化道重建方式对患者手术情况、术后恢复情况及围手术期并发症等的影响。n 结果:重叠式三角吻合组60例患者中男性32例,女性28例,年龄(57.3±10.4)岁,BMI为(25.0±3.1)kg/mn 2。传统三角吻合组55例患者中男性31例,女性24例,年龄(56.7±9.9)岁,BMI为(24.4±2.9)kg/mn 2。两组的性别、年龄、BMI、美国麻醉医师协会(ASA)分级、TNM分期、术前腹部手术史、术前新辅助化疗史以及术前营养状况的指标(血红蛋白、淋巴细胞计数、前白蛋白及白蛋白等)等资料比较,差异均无统计学意义(均n P>0.05)。两组所有患者均获得Rn 0切除,无中转开腹及转为腹腔外吻合患者。重叠式三角吻合组消化道重建时间少于传统三角吻合组[(15.1±1.7)min比(15.9±2.4)min],差异有统计学意义(n t=-2.053,n P=0.042)。而两组患者手术时间、术中出血量、手术切口长度、肿瘤大小、近远切缘距离、淋巴结清扫数目、术后首次下床活动时间、术后住院时间比较,差异均无统计学意义(均n P>0.05)。但重叠式三角吻合组术后首次排气时间[(1.5±0.5)d比(1.7±0.5)d,n t=-2.028,n P=0.045]和首次排粪时间[(3.1±0.6)d比(3.4±0.7)d,n t=-2.095,n P=0.039]均短于传统三角吻合组,差异均有统计学意义(均n P0.05). All the patients in both groups received R0 resection without conversion to open laparotomy or conversion to extra-abdominal anastomosis. The digestive tract reconstruction time of the ODA group was significantly shorter than that of the control group [(15.1±1.7) minutes vs. (15.9±2.4) minutes,n t=-2.053, n P=0.042]. There were no statistically significant differences in the total operation time, intraoperative blood loss, length of skin incision, tumor size, proximal and distal margins, harvested lymph nodes, postoperative first ambulatory time, and postoperative hospital stay (all n P>0.05). However, the time to the first flatus and the first defecation in the ODA group was significantly shorter as compared to control group [(1.5±0.5) days vs. (1.7±0.5) days,n t=-2.028, n P=0.045; (3.1±0.6) days vs. (3.4±0.7) days, n t=-2.095, n P=0.039], indicating faster intestinal function recovery in patients with ODA. The morbidity of postoperative complication was 6.7% (4/60) in the ODA group and 7.3% (4/55) in the control group and no significant difference was found (χn 2=0.016, n P=0.898). Two cases of incision infection, 1 case of lung infection, and 1 case of intra-abdominal infection occurred in the ODA group, while 3 cases of lung infection and 1 case of intra-abdominal infection occurred in the control group. All these complications were resolved after conservative treatment, and no secondary operation was performed due to complications.n Conclusion:Compared with the traditional delta-shaped anastomosis, ODA is associated with a faster recovery of postoperative intestinal function without increasing the morbidity of postoperative complications, and has the satisfactory short-term efficacy.