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目的:探讨急性有机磷农药中毒患者血糖、白细胞、中性粒细胞和C-反应蛋白水平的变化及临床意义。方法:患者入抢救室后,根据中毒的程度分为轻度、中度、重度3组,健康体检者作为对照组,分别抽静脉血检测血糖、白细胞、中性粒细胞和C-反应蛋白。结果:中度和重度中毒组血糖、白细胞、中性粒细胞和C-反应蛋白水平均显著高于对照组(P<0.01,P<0.05),轻度中毒组各项指标无显著差异。重度中毒组随病情加重,各项指标呈上升趋势,中度中毒组则随病情减轻,各项指标呈下降趋势。结论:急性有机磷农药中毒患者血糖、白细胞、中性粒细胞和C-反应蛋白水平的升高与中毒的程度呈正相关,血糖、白细胞、中性粒细胞和C-反应蛋白的水平越高,并发症及病死率也越高。这对指导治疗、减少并发症和降低病死率有一定意义。
Objective: To investigate the changes and clinical significance of blood glucose, leucocyte, neutrophil and C-reactive protein in patients with acute organophosphorus pesticide poisoning. Methods: After entering the emergency room, the patients were divided into mild, moderate and severe groups according to the degree of poisoning. The healthy subjects were taken as the control group, and blood glucose, leukocytes, neutrophils and C-reactive protein were detected by venous blood. Results: The levels of blood glucose, leucocyte, neutrophil and C-reactive protein in moderate and severe poisoning group were significantly higher than those in control group (P <0.01, P <0.05). There was no significant difference in mild poisoning group. Severe poisoning group with the aggravation of the disease, the indicators showed an upward trend in the moderate poisoning group with the disease reduced, the indicators showed a downward trend. Conclusion: The levels of blood glucose, leucocytes, neutrophils and C-reactive protein in patients with acute organophosphorus pesticide poisoning are positively correlated with the degree of poisoning. The higher the level of blood glucose, white blood cells, neutrophils and C-reactive protein, Complications and mortality are higher. This is a guide to treatment, reduce complications and reduce mortality has some significance.