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1952年King和Schumackcr报道脾切除后可发生凶险性切脾后感染(Overwhelming Post-splenectomy Infection)以后,人们开始认识到脾脏是一个具有重要免疫功能的脏器。通过研究,证实脾脏在细胞免疫和体液免疫中起着重要的作用。随着免疫学的迅速发展,人们对肿瘤免疫的问题日益重视,脾脏在肿瘤免疫中的作用也受到许多人的关注;对此国内甚少报道,国外的研究主要限于动物实验,结果颇不一致。现就这方面作一综述。
In 1952 King and Schumackcr reported that splenectomy could result in an infection after splenectomy (Overwhelming Post-splenectomy Infection). People began to realize that the spleen is an organ with important immune function. Through research, it was confirmed that the spleen played an important role in cellular immunity and humoral immunity. With the rapid development of immunology, people have paid more and more attention to the problem of tumor immunity. The role of the spleen in tumor immunity has also attracted the attention of many people; it is rarely reported in this country, and foreign studies are mainly limited to animal experiments, and the results are quite inconsistent. This is an overview.