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显微解剖发现犬主动脉和肺动脉间神经节丛(A-PGP)有大量神经节或神经元,注射烟碱100μg于30只犬的A-PGP,在完整心脏和去神经支配心脏均引出正性或负性变时性和变力性反应,心脏急性去神经支配后,反应频数降低。结论:烟碱可直接兴奋心脏表面节后交感神经元和副交感神经元,也可靠刺激传入神经元间接兴奋它们。
Micro-dissection revealed a large number of ganglion or neurons in the canine aorta and inter-pulmonary artery plexus (A-PGP). A-PGP injected 100 μg nicotine in 30 dogs elicited positive in intact and denervated hearts Sexual or negative variability and variable reaction, the heart of acute denervation, the reaction frequency decreased. CONCLUSIONS: Nicotine can directly excite sympathetic and parasympathetic postnatal ganglion neurons and also indirectly stimulate them by stimulating afferent neurons.