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本文对硬膜外注射康宁克通A治疗腰椎间盘突出症致血压改变12例病例分析，其血压改变的发生时间为3～5分钟，症状消退时间为30～60分钟。不良反应有：一过性体位性低血压者5例，高血压件低烧者3例，颅内压增高者4例，经及时对症处理，症状缓解。提示应用康宁克通A作硬膜外注射时，应根据患者性别、年龄、体重等差异．采取个体化给药，适当降低康宁克通A剂量，减慢注射速度，在完成硬膜外注射后，应静卧10分钟．以防止和减少不良反应的发生。
In this paper, 12 cases of changes of blood pressure induced by epidural injection of Cunningyl A in the treatment of lumbar disc herniation were analyzed. The time of blood pressure change was 3 to 5 minutes and the symptom subsidence time was 30 to 60 minutes. Adverse reactions are: transient orthostatic hypotension in 5 cases, hypertension in 3 cases, increased intracranial pressure in 4 cases, the timely symptomatic treatment, the symptoms were relieved. Prompt application of Cunningham A for epidural injection, should be based on the patient’s gender, age, weight and other differences. To individualized administration, appropriate reduction of dose of Corning g A, slow down the injection rate, after completing the epidural injection, should be lying 10 minutes. To prevent and reduce the occurrence of adverse reactions.