论文部分内容阅读
将40只金黄地鼠随机分为4组，每组10只，1组用于空白对照，其余3组用0．5％二甲基苯并蒽丙酮溶液涂布颊囊粘膜，每周3次诱癌，至第6、9、12周时颊粘膜依次表现为白斑、原位癌和浸润癌。在诱癌全过程中动态检测红细胞免疫功能和血浆纤维蛋白原含量。结果发现，癌变前两者均无变化，肿瘤生成后红细胞免疫功能下降、纤维蛋白原含量升高，此变化随肿瘤的继续生长而加剧。本文还对上述变化的原因进行了初步分析。
Forty golden hamsters were randomly divided into 4 groups with 10 in each group. One group was used for blank control, and the other 3 groups were coated with cheek pouch mucosa with 0.5% dimethylbenzanthracene acetone solution three times a week Induced cancer, to the 6th, 9th and 12th week, the buccal mucosa showed white spots, carcinoma in situ and infiltrating carcinoma. Dynamic detection of erythrocyte immune function and plasma fibrinogen content in the whole process of cancer induction. The results showed that there was no change in the two before carcinogenesis, erythrocyte immune function decreased after tumorigenesis, fibrinogen content increased, the change intensified with the continued growth of the tumor. The article also made a preliminary analysis of the reasons for the above changes.