目的　研究颞下颌关节紊乱综合症 (TMJD)患者的人格、应对方式与免疫功能的关系。方法　采用明尼苏达多项人格调查表 (MMPI)、生活事件量表、特质应对问卷对确诊病人 31例和匹配对照组 30例进行个别心理测验 ,以放射免疫法测定两组被试唾液中IgA含量。 结果　颞下颌关节紊乱综合症患者MMPI诸指标明显高于正常对照组 ,差异有显著性 (P <0 .0 5 ,P <0 .0 1) ,其中有 10例患者的临床量表高于全国常模正常值 ;患者组的正性生活事件明显低于对照组 ,负性生活事件明显高于对照组 ,差异有显著性 (P <0 .0 5 ,P <0 .0 1) ;患者组正性应对方式得分低于对照组 ,负性应对方式得分高于对照组 ,差异有显著性 (P <0 .0 1) ;病人组唾液中IgA含量明显低于对照组 ,差异有显著性 (P <0 .0 1)。结论　颞下颌关节紊乱综合症患者所具有的人格偏离、不良生活事件和负性应对方式导致的更强、更持久的应激与免疫功能的紊乱是疾病的重要原因 Objective To study the relationship between personality, coping style and immune function in patients with temporomandibular disorder (TMJD). Methods The Minnesota Multiple Personality Inventory (MMPI), Life Events Scale and Traits questionnaire were used to examine the IgA levels in saliva of 31 subjects and 31 matched controls. The levels of IgA in saliva of the two groups were measured by radioimmunoassay. Results The indexes of MMPI in patients with temporomandibular disorder were significantly higher than those in the control group (P <0.05, P <0.01), and the clinical scales of 10 patients were higher than those in the whole country Normotensive group; normal life events in patients group were significantly lower than those in control group, negative life events were significantly higher than those in control group, the difference was significant (P <0.05, P <0.01); patient group The score of positive coping style was lower than that of the control group, and the score of negative coping style was higher than that of the control group (P <0.01). IgA level in saliva of the patient group was significantly lower than that of the control group P <0 .0 1). Conclusion Personality deviation, adverse life events and negative coping styles in patients with temporomandibular disorders are the more important and persistent causes of stress and disturbance of immune function