对动脉粥样硬化深入系统的研究始于20世纪50年代,相继开展了流行病学、临床和实验室研究,从群体水平到整体、器官水平再到细胞、分子水平,直至现在的基因组和功能基因组水平,临床和实验室研究的很多成果也得到了群体研究的印证。人们逐渐取得共识:动脉粥样硬化是一个可以干预的过程,是一个由多种遗传因素和环境因素共同作用的结果。 In-depth system of atherosclerosis began in the 1950s, and epidemiological, clinical and laboratory studies were conducted one after another, ranging from population level to overall, organ level to cell and molecular level, up to the present genome and function Genome levels, many of the outcomes of clinical and laboratory research, have also been corroborated by group studies. People gradually come to a consensus: atherosclerosis is an intervening process that is a result of multiple genetic and environmental factors.