论文部分内容阅读
目的探讨氩氦刀冷冻联合经尿道前列腺电切术(TURP)治疗中叶明显突入膀胱的前列腺癌的安全性和近期疗效。方法采用经直肠超声引导下经会阴前列腺癌氩氦刀冷冻联合经尿道前列腺中叶切除术治疗中叶明显突入膀胱的初诊前列腺癌患者2例。术后2个月复查血前列腺特异抗原(PSA),以及盆腔CT或MRI。结果 2例患者手术均顺利完成,手术时间、冷冻复温时间、术中出血量分别为115min、50min、20ml,110min、52min、15ml。术后无明显血尿及导尿管堵塞等,2周后顺利拔除导尿管,未出现尿潴留及尿失禁。患者术前、术后2个月盆腔CT或MRI对比显示:前列腺明显缩小,突入膀胱的中叶已消失。2例患者术后2个月复查PSA分别为0.909、0.26ng/ml。结论氩氦刀冷冻联合TURP治疗中叶明显突入膀胱的前列腺癌安全可行,近期疗效确切。
Objective To investigate the safety and short-term efficacy of cryoablation combined with transurethral resection of the prostate (TURP) in the treatment of prostate cancer with obvious midcourse invasion into the bladder. Methods Two patients with newly diagnosed prostate cancer who had obvious midclavicular protrusion into the bladder underwent transrectal ultrasound-guided cryoablation of the perineal prostate with cryoablation and transurethral resection of the prostate. Blood prostate specific antigen (PSA) and pelvic CT or MRI were reviewed 2 months after surgery. Results The operation of two patients were successfully completed. The operation time, cryogenic rewarming time and intraoperative blood loss were 115min, 50min, 20ml, 110min, 52min and 15ml respectively. No obvious postoperative hematuria and catheter blockage, 2 weeks after the successful removal of the catheter, there is no urinary retention and urinary incontinence. Patients preoperative and postoperative 2 months pelvic CT or MRI contrast: significantly reduced prostate, the middle of the bladder has disappeared. Two patients after 2 months of review PSA were 0.909,0.26ng / ml. Conclusions Argon-helium-knife cryosurgery combined with TURP is safe and feasible in the treatment of prostate cancer with obvious invasion into the middle of the bladder. The recent curative effect is definite.