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目的 了解江苏省新生儿碘营养状况。方法 于 1997年 3~ 5月在全省范围按 PPS法抽取 30个点 ,检测新生儿脐带全血促甲状腺激素 (TSH)水平。结果 检测新生儿脐带血 86 2份 ,TSH中位数为 3.5 35m U/ L,>5 m U/ L 的脐血样品数占总样品数的 31.7% ,与 1995年 (4 1.4% )相比有所下降 (P <0 .0 5 ) ,但仍远高于“新生儿 TSH>5 m U/ L 的比例 <3%”的碘缺乏病消除标准。同时发现新生儿 TSH水平与 8~ 10岁儿童甲状腺肿大率及尿碘水平存在着严重分离现象。结论 江苏省新生儿碘营养状况有所改善 ,但仍存在碘营养不足。建议加强对孕妇等特需人群的补碘工作 ,并尽快研究出与国际接轨的新生儿脐带血 TSH切点值。
Objective To understand the status of neonatal iodine nutrition in Jiangsu Province. Methods From March to May 1997, 30 points were detected by PPS in the whole province to detect the level of thyroid stimulating hormone (TSH) in neonatal umbilical cord blood. Results There were 862 neonatal umbilical cord blood samples, with a median TSH of 3.5 35 mU / L and a cord blood sample> 5 mU / L, accounting for 31.7% of the total sample number, compared with 1995 (4 1.4%) (P <0.05), but still much lower than the "neonatal TSH> 5 mU / L ratio <3% of iodine deficiency deficiency elimination criteria. Also found that neonatal TSH levels and 8 to 10-year-old children with goiter and urinary iodine levels there is a serious separation phenomenon. Conclusion The iodine nutrition status of neonates in Jiangsu Province has been improved, but iodine deficiency still exists. It is suggested to strengthen iodine supplement work for pregnant women and other special needs groups as soon as possible and to study the value of cord blood TSH cut-off point of newborn with international standards as soon as possible.