雌激素受体存在于心血管、泌尿生殖道、骨、脑、眼、皮肤等组织中 ,雌激素与之结合发挥重要作用。绝经后上述器官发病增加 ,近期主要出现潮热、多汗 ,远期常见心血管疾病和骨质疏松及泌尿生殖道症状。雌激素补充治疗 (ＨＲＴ)能有效防治多种疾病 ,但对某些组织的不良反应也应重 Estrogen receptors exist in the cardiovascular, genitourinary tract, bone, brain, eye, skin and other tissues, estrogen and play an important role. Postmenopausal increased incidence of these organs, the recent main hot flashes, sweating, long-term common cardiovascular disease and osteoporosis and genitourinary tract symptoms. Estrogen replacement therapy (HRT) can effectively prevent and treat many diseases, but adverse reactions to some tissues should also be heavy