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新近对有机汞的遗传作用已引起特别重视。主要由于在植物、昆虫及动物实验中证实了对细胞分裂过程的作用(c-有丝分裂)、染色体断裂及基因突变。在甲基汞接触者淋巴细胞的细胞学研究中亦已获得证实。红葱根及果蝇的实验表明:有机汞、包括烷基汞对染色体成双倍时的细胞纺锤体有影响,或者在有丝分裂时个别染色体分配缺陷。Umeda等用各种有机汞作HeLa细胞组织培养的实验,获得某些c-有丝分裂作用,但没有提到剂量与作用之间的定量关系。Fiskesj(?)进行了氯化甲基汞对人淋巴细胞培养的作用的研究。引起明显的c-有丝分裂的最低剂量(在培养基中)为1～
The recent genetic effects of organic mercury have drawn particular attention. Mainly due to the role of the cell division process (c-mitosis), chromosome rupture and gene mutation confirmed in plant, insect and animal experiments. It has also been confirmed in cytological studies of lymphocytes exposed to methylmercury. Experiments in Onion and Drosophila show that organic mercury, including Alkylmercury, has an effect on the cellular spindle when chromosomes are doubled, or on individual chromosomes at mitosis. Umeda et al. Used various organic mercury for HeLa cell tissue culture experiments to obtain some c-mitosis but did not mention the quantitative relationship between dose and action. Fiskesj (?) Conducted a study of the effect of methylmercury chloride on human lymphocyte culture. The lowest dose (in medium) that caused significant c-mitosis was 1 ~