目的探讨吉兰 -巴雷综合征 (GBS)伴发多脏器功能障碍综合征 (MODS)的原因及防治。方法结合文献分析 GBS伴发 MODS的可能机理。结果认为本组病例均可能是机体遭受病毒感染后 ,在神经 -内分泌 -免疫失衡条件下 ,以免疫为中介引起的全身性炎症反应 ,继而引起多脏器功能障碍。结论 GBS可以伴发 MODS,对老年重症患者应预防和早期发现、早期治疗 MODS,降低病死率 Objective To investigate the causes and prevention of multiple organ dysfunction syndrome (MODS) associated with Guillain-Barre syndrome (GBS). Methods Combined with literature analysis of possible mechanism of GBS associated with MODS. The results suggest that this group of patients may be infected with the body after the virus in the neuroendocrine-immune imbalance conditions, immune-mediated systemic inflammation caused by, and then cause multiple organ dysfunction. Conclusion GBS can be associated with MODS, prevention and early detection of elderly patients with severe disease, early treatment of MODS, reduce mortality