目的 :探讨人体进入高原低氧环境初期和移居 6个月与居住 2年后血型与血氧饱和度 (SaO2 )之间的内在关系 ,为高原低氧生理积累资料 ;方法 :对初入海拔 5 3 80m 3天～ 7天和居住 6个月的 198名边防军人及移居海拔 43 0 0m 2年的 48名健康青年在静息状态下进行ABO血型鉴定同时检测SaO2 ;结果 :初入海拔 5 3 80m 3天～ 7天的健康青年O、A血型的SaO2 含量显著高于B、AB型血的青年 (P <0 .0 1或P <0 .0 5 ) ,B型血与AB型血之间的SaO2 含量无显著性差异 (P >0 .0 5 ) ,海拔 5 3 80m移居 6个月的青年A、O、B、AB型血之间的SaO2 含量无显著性差异 (P >0 .0 5 ) ,海拔 43 0 0m移居 2年者O、A、B型血SaO2含量显著高于AB型血者 (P <0 .0 1) ,O、A、B型血之间的SaO2 含量无显著性差异 (P >0 .0 5 ) ;结论 :O、A型血者初入高海拔地区后SaO2 含量高于B、AB型血者 ,提示O、A型血者高原早期适应性较B、AB型血者佳。海拔 5 3 80m移居 6个月和 43 0 0m移居 2年后 ,A、O、B、AB四种血型者均可达到低氧环境的适应和习服 ,但AB型血SaO2 含量仍低于A、O、B血型者 ,随着低氧的持续暴露 ,这种现象渐趋明显。 Objective: To explore the relationship between the blood type and the oxygen saturation (SaO2) in the early stage of hypoxia and altitude of 6 months after living in the plateau and living for 2 years, and to accumulate data for hypoxia physiology in the plateau. Methods: A total of 198 border policemen from 3 days to 7 days and 6 months of age and 48 healthy young people who migrated to an altitude of 4300m2 were tested for ABO blood group type at the same time while SaO2 was detected. Results: 80m 3 days to 7 days of healthy youth O, A blood SaO2 content was significantly higher than the B, AB blood type youth (P <0 1 or P <0 05), blood type B and type AB blood There was no significant difference in the content of SaO2 among young A, O, B, and AB blood samples (P> 0.05). (P <0.01). The content of SaO2 in O, A and B blood was significantly higher than that in AB blood (P <0.01), and the content of SaO2 in O, A and B blood was (P0.05) .Conclusion: The content of SaO2 in type A and type A blood after entering high altitude area is higher than that of type B and type AB blood, which indicates that the adaptability of type O and type A blood is higher than that of type B AB good blood type. After two years of migration at 5 3 80m above sea level and 6 months after migration at 43 0 0m, all four blood types A, O, B and AB were able to adapt and accustom to hypoxia. However, the content of SaO2 in AB blood was still lower than A , O, B blood type, with the sustained exposure to hypoxia, this phenomenon becomes apparent.