目的比较回流法和超声法从中药常山中提取常山乙素的提取效果。方法采用高效液相色谱法测定常山乙素含量,以浸膏得率和常山乙素含量作为评价指标。结果回流法和超声提取法浸膏平均得率分别为10.11%和12.87%;浸膏中常山乙素平均含量分别为0.160%和0.181%。结论回流法和超声法提取工艺具有省时、操作简便和提取率高等优点,超声法相对更好一点。 Objective To compare the extraction efficiency of Changshen B with traditional Chinese medicine Changshan by reflux and sonication. Methods The content of Corynebacterium was determined by high performance liquid chromatography (HPLC). The extraction yield and the content of Changsan B were used as evaluation indexes. Results The average yield of extract was 10.11% and 12.87% respectively by reflux method and ultrasonic extraction method. The average content of Changsan B in extract was 0.160% and 0.181% respectively. Conclusion The method of reflux and ultrasonic extraction have the advantages of saving time, simple operation and high extraction rate, and the ultrasonic method is relatively better.