目的:研究清凉膏的抗炎、镇痛作用。方法:采用二甲苯致小鼠耳肿胀、角叉菜胶致大鼠足肿胀、热板刺激、冰醋酸刺激小鼠扭体等方法研究清凉膏的抗炎及镇痛作用。结果:清凉膏中、大剂量组能明显抑制二甲苯致小鼠耳肿胀;抑制大鼠足肿胀;药后6h能明显延长小鼠疼痛反应时间,减少小鼠扭体次数。结论:清凉膏具有显著的抗炎、镇痛作用。 Objective: To study the anti-inflammatory and analgesic effects of Qingliang Paste. METHODS: The anti-inflammatory and analgesic effects of Qingliang Paste were studied by xylene-induced mouse ear swelling, foot swelling caused by carrageenan, hot plate stimulation, and acetic acid-stimulated mouse writhing. RESULTS: The middle and large doses of Qingliang Ointment could significantly inhibit xylene-induced ear swelling of the mice and inhibit the swelling of the paws of the rats. At 6 hours after the injection, the pain reaction time of the mice was significantly prolonged, and the number of writhing of the mice was reduced. Conclusion: Qingliang cream has significant anti-inflammatory and analgesic effects.