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目的探讨尿动力学检查在间质性膀胱炎疗效观察中的应用。方法对26例采用不同方法进行治疗的间质性膀胱炎患者治疗前、后进行尿动力学检查。这些患者分别接受口服药物治疗、膀胱灌注治疗、膀胱水扩张治疗及膀胱逼尿肌内A型肉毒毒素注射等方法之一或联合治疗,在治疗前、后接受1次或2次以上尿动力学检查,同时,在治疗前后相同时间点进行盆腔疼痛和尿频/尿急症状评分(PUF)。尿动力学检查检测指标包括残余尿量、最大尿意容量、初始尿意容量、膀胱顺应性、最大尿道压。分别比较每项参数治疗前、后改善情况。对比患者主观指标PUF评分所得出的改善程度,比较并分析尿动力学参数与PUF评分的一致程度。结果最大尿意容量与PUF评分的一致性比较:rs=0.879,P<0.05;初始尿意容量与PUF评分的一致性比较:rs=0.545,P<0.05;膀胱顺应性与PUF评分的一致性比较:rs=0.529,P<0.05;残余尿量及最大尿道压与PUF评分之间无统计学意义。结论尿动力学检查在间质性膀胱炎疗效观察中可发挥重要作用,为评估相关治疗方法的疗效,及患者后续治疗方案选择提供客观的依据;各尿动力学参数中,最大尿意容量、初始尿意及膀胱顺应性三者参考意义最大。
Objective To investigate the application of urodynamic examination in the observation of the efficacy of interstitial cystitis. Methods Twenty-six patients with interstitial cystitis treated by different methods were examined before and after treatment. These patients received oral drug treatment, bladder irrigation treatment, bladder water expansion treatment and bladder detrusor A botulinum toxin injection or other methods of one or combination of treatment before treatment, after receiving more than one or two urine At the same time, pelvic pain and frequent urination / urgency score (PUF) were assessed at the same time point before and after treatment. Urodynamic test indicators include residual urine volume, maximum urinary volume, initial urinary volume, bladder compliance, maximum urethral pressure. Compare each parameter before and after treatment to improve the situation. Comparing the degree of improvement obtained by subjective index PUF score of patients, the consistency of urodynamic parameters and PUF score was compared and analyzed. Results The consistency of maximum urinary volume and PUF score was compared: rs = 0.879, P <0.05; Consistency of initial urinary volume and PUF score: rs = 0.545, P <0.05; Comparing the consistency between bladder compliance and PUF score: rs = 0.529, P <0.05; residual urine volume and maximum urethral pressure and PUF score was not statistically significant. Conclusions Urodynamic examination can play an important role in the observation of the curative effect of interstitial cystitis and provide an objective basis for assessing the curative effect of the relevant treatment methods and the selection of follow-up treatment options. In each urodynamic parameter, the maximum urinary volume, Urgency and urinary bladder compliance refer to the three most significant.