PHA刺激实验小动物的胸腺细胞通常呈低应答性。对人胸腺细胞的转化能力尚有争论。作者已报导,胸腺的一种体液因子(HTECM)能提高年轻供者胸腺细胞对Con A和PHA的应答。PHA似能提高高龄者胸腺细胞的应答,但此应答不能经HTECM进一步增高。为此,作者对成人胸腺细胞致裂原的应答及HTECM的敏感性作了进一步的研究。 Thymocytes of PHA-stimulated experimental animals usually exhibit low responsiveness. The ability to transform human thymocytes remains controversial. The authors have reported that a thymus humoral factor (HTECM) enhances the responsiveness of young donor thymocytes to Con A and PHA. PHA seems to increase the response of elderly thymocytes, but this response can not be further increased by HTECM. To this end, the author of adult thymus cell response to the original crack and HTECM sensitivity for further study.