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目的探讨影响临床药物流产效果的相关因素。方法选取2013年8月至2014年10月辽宁省海城市中医院接诊的230例早孕者作为研究对象,均进行临床药物流产,统计早孕者药物流产的效果,并分析年龄、既往剖宫产史、体重指数、子宫位置和孕囊直径对药物流产效果的影响。结果 230例药物流产早孕者中,完全流产211例,药物流产失败19例,失败率为8.3%(19/230);年龄≥35岁早孕者药物流产失败率明显高于年龄<35岁,差异有统计学意义(P<0.05);既往有剖宫产史早孕者药物流产失败率明显高于无剖宫产史,差异有统计学意义(P<0.05);子宫后倾后屈者早孕者药流失败率明显高于子宫前位和水平位,差异有统计学意义(P<0.05);体重指数≥25 kg/m2早孕者的药物流产失败率明显高于体重指数<25 kg/m2,差异有统计学意义(P<0.05);孕囊直径1.5 cm≤孕囊直径≤3 cm早孕者药物失败率明显低于其他患者,差异有统计学意义(P<0.05)。结论年龄越小、无剖宫史、子宫前位和水平位、体重指数低且孕囊直径1.5 cm≤孕囊直径≤3 cm的患者,药物流产效果好。
Objective To explore the influencing factors of abortion effect of clinical medicine. Methods A total of 230 pregnant women admitted to Haicheng Hospital of Traditional Chinese Medicine from August 2013 to October 2014 were enrolled in this study. Clinical abortion and statistical medical abortion were performed respectively. Age, previous cesarean section History, body mass index, uterine position and gestational sac diameter on the effect of medical abortion. Results Of the 230 cases of abortion with early pregnancy, 211 cases were completely aborted and 19 cases were aborted with drug abortion. The failure rate was 8.3% (19/230). The failure rate of medical abortion was significantly higher than that of 35 years old (P <0.05). The failure rates of medical abortion in those with previous history of cesarean section were significantly higher than those without history of cesarean section (P <0.05) The failure rate of medical abortion was significantly higher than that of anterior uterus and horizontal position, the difference was statistically significant (P <0.05). The rate of medical abortion was significantly higher than that of body mass index <25 kg / m2 in body mass index> 25 kg / m2 (P <0.05); the gestational sac diameter of 1.5 cm ≤ gestational sac diameter ≤ 3 cm in early pregnancy drug failure rate was significantly lower than other patients, the difference was statistically significant (P <0.05). Conclusions The smaller the age, no history of cesarean section, anterior uterine and horizontal position, low body mass index and gestational sac diameter of 1.5 cm ≤ gestational sac diameter ≤ 3 cm, the drug abortion effect is good.