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目的用平阳霉素联合地塞米松瘤内注射治疗口腔颌面部海绵状血管瘤,观察其疗效及不良反应。方法平阳霉素8mg+地塞米松5mg瘤内注射,根据肿瘤大小可单次或多次进行治疗。结果共治疗口腔颌面部海绵状血管瘤85例,经过10～24个月随访,治愈60例(70.59%),基本治愈20例(23.53%),有效5例(5.88%),治愈和基本治愈80例(94.12%)。不良反应主要为低中度发热和轻度胃肠道反应,分别占11.76%、8.24%。结论此方法最大限度地保留了颌面部的正常形态和功能,具有疗程短、疗效好的优点,而且操作简便,安全有效,毒副作用少。
Objective To treat intraoral and maxillofacial cavernous hemangiomas with pingyangmycin combined with dexamethasone intratumoral injection to observe the curative effect and adverse reactions. Methods Pingyangmycin 8mg + dexamethasone 5mg intratumoral injection, according to tumor size can be single or multiple treatment. Results A total of 85 cases of oral and maxillofacial cavernous hemangiomas were treated. After 10 to 24 months follow-up, 60 cases (70.59%) were cured, 20 cases (23.53%) were cured, 5 cases (5.88%) were cured, 80 cases were cured (94.12%). Adverse reactions were mainly mild to moderate fever and mild gastrointestinal reactions, accounting for 11.76% and 8.24%, respectively. Conclusion This method preserves the normal morphology and function of maxillofacial region to the maximum extent and has the advantages of short course of treatment and good curative effect. The method is simple, safe and effective with few side effects.